Structure-Based Design of Dendritic Peptide Bolaamphiphiles for siRNA Delivery
نویسندگان
چکیده
منابع مشابه
Structure-Based Design of Dendritic Peptide Bolaamphiphiles for siRNA Delivery
Development of safe and effective delivery vectors is a critical challenge for the application of RNA interference (RNAi)-based biotechnologies. In this study we show the rational design of a series of novel dendritic peptide bolaamphiphile vectors that demonstrate high efficiency for the delivery of small interfering RNA (siRNA) while exhibiting low cytotoxicity and hemolytic activity. Systema...
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ژورنال
عنوان ژورنال: ACS Central Science
سال: 2015
ISSN: 2374-7943,2374-7951
DOI: 10.1021/acscentsci.5b00233